Description

4-Bromo-n-Cyclopropyl-3-Fluorobenzamide is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated benzamide structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting a range of therapeutic areas. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to incorporate cyclopropyl and halogenated aromatic motifs into new molecular entities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially those requiring a fluorinated and brominated aromatic core for bioactivity and metabolic stability.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical space.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel herbicides, fungicides, or insecticides where the cyclopropyl group can confer specific biological activity.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways due to its potential as a protein-binding motif.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing bespoke compounds for client projects.
• Academic Research: Employed in university and institutional laboratories for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	4-Bromo-n-Cyclopropyl-3-Fluorobenzamide
CAS No.	1249139-26-1
Molecular Formula	C10H9BrFNO
Molecular Weight	258.09 g/mol
Synonyms	4-Bromo-N-cyclopropyl-3-fluorobenzamide; 3-Fluoro-4-bromo-N-cyclopropylbenzamide; Benzamide, 4-bromo-N-cyclopropyl-3-fluoro-; N-Cyclopropyl-4-bromo-3-fluorobenzamide; 4-Bromo-3-fluoro-N-cyclopropylbenzamide; 1249139-26-1; AI3-63566
EINECS	Contact for details

Quality Control

Our 4-Bromo-n-Cyclopropyl-3-Fluorobenzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatograms and spectral data are provided for every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.