Description

1-Acetyl-3-Methylpyrrolidine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a defined stereochemical structure. This compound is critical for the synthesis of complex active pharmaceutical ingredients (APIs), particularly in the development of novel therapeutics. It is primarily sought by research institutions and manufacturers in the pharmaceutical and biotechnology sectors for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially those targeting neurological and metabolic disorders.
• Protease Inhibitor Research: Used in the development of inhibitors for various proteolytic enzymes.
• Peptidomimetic Chemistry: Serves as a constrained scaffold for designing peptide analogs with enhanced stability and bioavailability.
• Medicinal Chemistry R&D: Employed in structure-activity relationship (SAR) studies and lead optimization processes.
• Chemical Biology Probes: Utilized in the creation of tool compounds for studying biological pathways and target validation.
• Custom Synthesis: A starting material for the contract manufacturing of specialized fine chemicals and custom APIs.

Basic Information

Product Name	1-Acetyl-3-Methylpyrrolidine-2-Carboxylic Acid
CAS No.	1248550-79-9
Molecular Formula	C9H15NO3
Molecular Weight	185.22 g/mol
Synonyms	1-Acetyl-3-methylpyrrolidine-2-carboxylic acid; 3-Methyl-1-acetylpyrrolidine-2-carboxylic acid; (2S,3S)-1-Acetyl-3-methylpyrrolidine-2-carboxylic acid; (2S,3S)-3-Methyl-1-(oxoacetyl)pyrrolidine-2-carboxylic acid; 2-Carboxy-3-methyl-1-acetylpyrrolidine; AMCA; A related IUPAC name: 1-acetyl-3-methylpyrrolidine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-Acetyl-3-Methylpyrrolidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical R&D and cGMP manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for prolonged operations to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.