Description

Benzonitrile, 5-Bromo-3-Fluoro-2-Methoxy- is a high-purity, multi-functional aromatic nitrile derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its value lies in its unique substitution pattern, which provides multiple reactive sites for selective functionalization, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and pesticides, leveraging its halogen and methoxy groups for bioactivity.
• Material Science Research: Serves as a precursor for functionalized polymers, liquid crystals, and organic electronic materials due to its aromatic core and polar nitrile group.
• Chemical Synthesis: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution (SNAr) to introduce complex substituents.
• Dye and Pigment Intermediate: Utilized in the synthesis of specialized dyes and pigments where bromo and fluoro substituents alter color and stability properties.

Basic Information

Product Name	Benzonitrile, 5-Bromo-3-Fluoro-2-Methoxy-
CAS No.	1247885-38-6
Molecular Formula	C8H5BrFNO
Molecular Weight	230.04 g/mol
Synonyms	5-Bromo-3-fluoro-2-methoxybenzonitrile; 2-Methoxy-5-bromo-3-fluorobenzonitrile; 3-Fluoro-5-bromo-2-methoxybenzonitrile; 2-Methoxy-3-fluoro-5-bromobenzonitrile; Benzonitrile, 3-fluoro-5-bromo-2-methoxy-; 1247885-38-6
EINECS	Contact for details

Quality Control

Our Benzonitrile, 5-Bromo-3-Fluoro-2-Methoxy- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment ensures the material is suitable for demanding applications in research and cGMP-compliant synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥98.0%
Purity (GC)	≥97.0%
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.