Description

(S)-1-[(Rp)-2-(Dicyclohexylphosphino)Ferrocenyl]Ethyldi-tert-Butylphosphine is a highly specialized, chiral ferrocenyl phosphine ligand, a cornerstone in modern asymmetric catalysis. Its value lies in enabling the precise control of stereochemistry in critical bond-forming reactions, leading to the efficient production of enantiomerically pure intermediates. This ligand is essential for researchers and process chemists in the pharmaceutical, agrochemical, and fine chemical industries developing novel active ingredients and high-value specialty chemicals.

Application

• Asymmetric Hydrogenation: A premier ligand for the enantioselective reduction of prochiral olefins, ketones, and imines, crucial for synthesizing chiral alcohols and amines in pharmaceutical APIs.
• Asymmetric Cross-Coupling Reactions: Facilitates C-C and C-X bond formations with high enantiomeric excess, used in constructing complex molecular architectures.
• Pharmaceutical Intermediate Synthesis: Key catalyst component for producing enantiopure building blocks for drug candidates targeting CNS disorders, oncology, and infectious diseases.
• Agrochemical Manufacturing: Enables the synthesis of chiral herbicides, fungicides, and plant growth regulators with improved efficacy and environmental profile.
• Fine Chemical and Fragrance Production: Used to create high-value chiral compounds for flavors, fragrances, and advanced materials.
• Academic and Process R&D: A vital tool for methodology development and scaling up asymmetric transformations from lab to pilot plant.

Basic Information

Item	Details
Product Name	(S)-1-[(Rp)-2-(Dicyclohexylphosphino)Ferrocenyl]Ethyldi-tert-Butylphosphine
CAS No.	1246841-00-8
Molecular Formula	C34H52FeP2
Molecular Weight	578.57 g/mol
Synonyms	(S,Rp)-Josiphos SL-J009-1; (S)-1-[(R)-2-(Dicyclohexylphosphino)ferrocenyl]ethyldi-tert-butylphosphine; Josiphos SL-J009-1; (S)-1-[(R)-2-(Dicyclohexylphosphino)ferrocenyl]ethyl-di-tert-butylphosphine; (S)-1-[(R)-2-(Dicyclohexylphosphanyl)ferrocenyl]ethyl-di-tert-butylphosphane; (S)-1-[(R)-2-(Dicyclohexylphosphino)ferrocenyl]ethyl-di-tert-butylphosphine; SL-J009-1; (S)-1-[(R)-2-(Dicyclohexylphosphino)ferrocenyl]ethyldi(tert-butyl)phosphine
EINECS	Contact for details

Quality Control

Every batch of our chiral phosphine ligands is produced and tested under strict quality management to ensure exceptional purity and performance consistency. We provide comprehensive Certificates of Analysis (COA) detailing purity, chiral purity (enantiomeric excess), and key impurity profiles, supported by advanced analytical techniques including HPLC, NMR, and elemental analysis. Our commitment to cGMP and ISO 9001 standards guarantees reliable material for your most demanding catalytic applications.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C in a cool, dry place. Due to its sensitivity to oxidation and moisture, containers should be flushed with inert gas after each opening to maintain stability and purity.

Specification

Item	Specification
Appearance	Orange to red-brown powder or crystals
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.