Description

2-(2-Amino-5-Bromobenzoyl)Pyridine-D4 is a deuterated aromatic compound featuring a brominated benzoylpyridine core, serving as a stable isotope-labeled analog for advanced research and development. This high-purity intermediate is critical for applications requiring precise molecular tracking and metabolic studies, offering superior reliability in analytical workflows. It is primarily utilized by pharmaceutical R&D teams, analytical laboratories, and specialty chemical manufacturers focused on developing and testing novel therapeutic agents and diagnostic tools.

Application

• As a stable isotope-labeled internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for quantitative bioanalysis.
• A key deuterated building block in the synthesis of novel pharmaceutical compounds, particularly for drug discovery programs targeting CNS disorders and oncology.
• Used in metabolic pathway studies and pharmacokinetic/pharmacodynamic (PK/PD) research to trace and quantify drug metabolites.
• Employed in the development and calibration of advanced analytical methods and reference materials for regulatory compliance and quality control.
• As a precursor for synthesizing deuterated fluorescent probes or ligands used in biochemical assays and imaging techniques.

Basic Information

Product Name	2-(2-Amino-5-Bromobenzoyl)Pyridine-D4
CAS No.	1246820-98-3
Molecular Formula	C12H4D4BrN2O
Molecular Weight	281.13 g/mol (for deuterated form)
Synonyms	2-(2-Amino-5-bromobenzoyl)pyridine-d4; 2-Amino-5-bromo-2'-pyridylbenzophenone-d4; 2-(2-Amino-5-bromophenyl)(pyridin-2-yl)methanone-d4; Deuteronated 2-(2-Amino-5-bromobenzoyl)pyridine; Deuterated ABBP; 2-Pyridinecarboxaldehyde, 2-amino-5-bromophenyl-d4 ketone; (2-Amino-5-bromophenyl)(pyridin-2-yl)methanone-d4; 1246820-98-3
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Amino-5-Bromobenzoyl)Pyridine-D4 is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. We guarantee high chemical purity and isotopic enrichment, supported by a detailed Certificate of Analysis (COA) that includes data from NMR (1H, 13C), Mass Spectrometry, and HPLC. Our quality assurance protocols are designed to meet the stringent requirements of research and pharmaceutical development, ensuring traceability and consistency for all global shipments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term storage, consider using inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (Deuteration Degree)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.