Description

Levamisole-D5 Hydrochloride is a high-purity, deuterium-labeled internal standard essential for precise quantitative analysis in advanced research and regulated testing environments. This stable isotope-labeled compound is critical for ensuring analytical accuracy and reliability in mass spectrometry-based methods, particularly when quantifying trace levels of the parent compound. It is primarily utilized by analytical laboratories, pharmaceutical R&D teams, and contract research organizations (CROs) engaged in method development, pharmacokinetic studies, and residue analysis.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for the accurate measurement of Levamisole in complex biological and environmental matrices.
• Pharmaceutical Metabolism Studies: Enables tracking and quantification of Levamisole and its metabolites in pharmacokinetic and drug metabolism research.
• Veterinary Drug Residue Analysis: Critical for developing and validating sensitive methods to detect and quantify Levamisole residues in food-producing animals and animal-derived products to ensure food safety.
• Forensic and Clinical Toxicology: Supports the accurate identification and quantification of Levamisole, which is sometimes found as an adulterant, in forensic and clinical diagnostic applications.
• Method Development and Validation: Serves as a key component in developing, optimizing, and validating robust analytical methods according to Good Laboratory Practice (GLP) and other regulatory guidelines.
• Quality Control in Reference Material Production: Employed in the preparation and certification of certified reference materials (CRMs) for quality assurance programs.

Basic Information

Product Name	Levamisole-D5 Hydrochloride
CAS No.	1246819-64-6
Molecular Formula	C₁₁H₁₇D₅ClN₂S
Molecular Weight	247.84 g/mol
Synonyms	(-)-Tetramisole-d5 Hydrochloride; (S)-(-)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b]thiazole-d5 Hydrochloride; Levamisole (phenyl-d5) Hydrochloride; Levamisole-d5 HCl; Deuterated Levamisole Hydrochloride; (S)-(-)-6-Phenyl-2,3,5,6-tetrahydroimidazo[2,1-b]thiazole-d5 Hydrochloride
EINECS	Contact for details

Quality Control

Our Levamisole-D5 Hydrochloride is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure the highest standards of isotopic purity and chemical identity. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) is provided, detailing isotopic enrichment, chemical purity, and confirming compliance with specifications for use as an internal standard.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (D-content)	≥98 atom % D
Chemical Purity	≥95.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.