Description

Methoxsalen-13Cd3 CAS NO 1246819-63-5 is a stable isotope-labeled analog of methoxsalen, where three hydrogen atoms are replaced by deuterium (²H) at the 13C position. This high-purity labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring analytical accuracy and reliability. It is primarily required by pharmaceutical research laboratories, contract research organizations (CROs), and analytical service providers engaged in pharmacokinetic studies, drug metabolism research, and bioanalytical method development.

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of methoxsalen in complex biological matrices such as plasma, serum, and urine.
• Pharmacokinetic and Bioavailability Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) profiles.
• Drug Metabolism Research: Used to identify and quantify metabolites, facilitating a deeper understanding of metabolic pathways.
• Bioanalytical Method Development and Validation: Serves as a key component in establishing robust, reproducible, and regulatory-compliant analytical methods.
• Clinical Research and Therapeutic Drug Monitoring (TDM): Supports studies on the efficacy and safety of methoxsalen-based treatments, such as for vitiligo and psoriasis (PUVA therapy).
• Quality Control in Pharmaceutical Manufacturing: Can be utilized in impurity profiling and ensuring batch-to-batch consistency of active pharmaceutical ingredients (APIs).

Basic Information

Item	Detail
Product Name	Methoxsalen-13Cd3
CAS No.	1246819-63-5
Molecular Formula	C12H5D3O4 (C12H8O4 with three ²H at the 13C position)
Molecular Weight	Contact for details
Synonyms	8-Methoxypsoralen-13Cd3; 8-MOP-13Cd3; 9-Methoxy-7H-furo[3,2-g]chromen-7-one-13Cd3; Xanthotoxin-13Cd3; Ammoidin-13Cd3; Meladinine-13Cd3; Oxsoralen-13Cd3; [²H3]-Methoxsalen
EINECS	Contact for details

Quality Control

Our Methoxsalen-13Cd3 is manufactured under strict quality control protocols to ensure the highest isotopic and chemical purity required for sensitive analytical applications. Each batch is characterized by advanced spectroscopic and chromatographic techniques, including NMR, HPLC, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, chemical purity, and analytical data is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Identification (MS)	Conforms to structure
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Chemical Purity (HPLC)	≥ 98.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.