Description

Mabuterol-D9 Hydrochloride is a high-purity, deuterium-labeled internal standard critical for modern analytical chemistry. This stable isotope-labeled compound is essential for ensuring the accuracy and reliability of quantitative mass spectrometry analyses. It is primarily used by pharmaceutical R&D laboratories, contract research organizations (CROs), and regulatory testing facilities for method development, validation, and bioanalytical studies.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in the analysis of Mabuterol and related compounds in biological matrices (plasma, urine, tissue).
• Pharmaceutical Metabolism and Pharmacokinetics (DMPK) Studies: Enables precise tracking and quantification of the parent drug in absorption, distribution, metabolism, and excretion (ADME) research.
• Doping Control and Forensic Analysis: Supports the accurate detection and confirmation of β-2 agonist misuse in sports and forensic toxicology.
• Veterinary Drug Residue Testing: Facilitates compliant monitoring of drug residues in food-producing animals to ensure food safety.
• Method Development and Validation: Serves as a critical tool for developing, optimizing, and validating robust analytical methods in compliance with ICH, FDA, and EMA guidelines.
• Clinical Trial Support: Provides reliable quantification for drug concentration monitoring in human clinical trials.

Basic Information

Product Name	Mabuterol-D9 Hydrochloride
CAS No.	1246819-58-8
Molecular Formula	C13H9D9Cl2N2O3 • HCl
Molecular Weight	382.69 g/mol (approx.)
Synonyms	Mabuterol-d9 HCl; 1-(4-Amino-3,5-dichlorophenyl)-2-(tert-butylamino)ethanol-d9 Hydrochloride; 4-Amino-3,5-dichloro-α-[[(1,1-dimethylethyl)amino]methyl]-benzenemethanol-d9 Hydrochloride; Mabuterol (methyl-d9) Hydrochloride; Mabuterol-d9 (HCl); Deuterated Mabuterol Hydrochloride; Internal Standard for Mabuterol
EINECS	Contact for details

Quality Control

Our Mabuterol-D9 Hydrochloride is manufactured under strict quality control protocols to ensure the highest isotopic purity and chemical integrity required for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing results for isotopic enrichment, chemical purity, and identity confirmation via advanced spectroscopic techniques. We support compliance with cGMP and ISO 9001 standards for research and diagnostic use.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥98.0%
Isotopic Purity (Deuterium Enrichment)	≥98.0 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.