Description

4-[(4,6-Dichloro-2-Pyrimidinyl)Amino]Benzonitrile-13C3 is a stable isotope-labeled analog of a key pyrimidine derivative, where three carbon atoms are replaced with the carbon-13 isotope. This compound is essential for use as an internal standard in quantitative mass spectrometry, providing unparalleled accuracy and reliability in analytical measurements. It is primarily utilized by researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental testing industries for method development, pharmacokinetic studies, and metabolite identification.

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of the unlabeled parent compound in complex biological matrices like plasma, urine, and tissue homogenates.
• Drug Metabolism and Pharmacokinetics (DMPK): Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) studies.
• Biomarker Analysis: Used in the development of sensitive assays for disease biomarker detection and validation.
• Environmental Fate Studies: Assists in tracing the degradation and transformation pathways of agrochemicals and pollutants.
• Pharmaceutical Impurity Profiling: Helps identify and quantify process-related impurities and degradants in active pharmaceutical ingredients (APIs).
• Clinical Research: Supports bioanalytical method validation for clinical trials, ensuring data meets regulatory standards.

Basic Information

Product Name	4-[(4,6-Dichloro-2-Pyrimidinyl)Amino]Benzonitrile-13C3
CAS No.	1246818-77-8
Molecular Formula	C1013C3H6Cl2N4
Molecular Weight	Contact for details
Synonyms	4-[(4,6-Dichloro-2-pyrimidinyl)amino]benzonitrile-13C3
Benzonitrile-13C3, 4-[(4,6-dichloro-2-pyrimidinyl)amino]-
4-(4,6-Dichloropyrimidin-2-ylamino)benzonitrile-13C3
2-[(4-Cyano-13C3-phenyl)amino]-4,6-dichloropyrimidine
4-(4,6-Dichloro-pyrimidin-2-ylamino)-benzonitrile-13C3
13C3-labeled 4-[(4,6-Dichloro-2-Pyrimidinyl)Amino]Benzonitrile
Stable Isotope Labeled DCPAB
EINECS	Contact for details

Quality Control

Every batch of 4-[(4,6-Dichloro-2-Pyrimidinyl)Amino]Benzonitrile-13C3 is manufactured and analyzed under strict quality systems. Our products undergo rigorous quality testing, including isotopic purity and chemical purity assays, to ensure compliance with the high standards required for analytical research. A comprehensive Certificate of Analysis (COA) detailing batch-specific results for identity, purity (HPLC), isotopic enrichment (MS), and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified and opened in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 99 atom % 13C
Isotopic Enrichment	≥ 99% on three labeled positions
Chemical Purity	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.