Description

n-Des(2-Pyridinyl)-n-(5-Hydroxymethyl-2-Thiazolyl) Lornoxicam is a key pharmaceutical intermediate and a structurally modified derivative of the non-steroidal anti-inflammatory drug (NSAID) Lornoxicam. This compound is of significant value for research and development in medicinal chemistry, particularly for exploring new anti-inflammatory and analgesic agents with potentially improved pharmacokinetic profiles. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of active pharmaceutical ingredients (APIs) focused on novel NSAID development.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel Lornoxicam analogs and related therapeutic compounds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new non-steroidal anti-inflammatory drugs (NSAIDs) with enhanced efficacy or reduced side effects.
• Analytical Reference Standard: Employed as a high-purity standard in HPLC, LC-MS, and other analytical methods for quality control and metabolic studies.
• API Development: Integral to the research and process development for new Active Pharmaceutical Ingredients targeting COX-1 and COX-2 inhibition.
• Preclinical Studies: Utilized in pharmacological and toxicological evaluations during the drug discovery pipeline.

Basic Information

Product Name	n-Des(2-Pyridinyl)-n-(5-Hydroxymethyl-2-Thiazolyl) Lornoxicam
CAS No.	1246818-50-7
Molecular Formula	C15H13N3O4S2
Molecular Weight	363.41 g/mol
Synonyms	Lornoxicam Impurity; Lornoxicam Derivative; Lornoxicam Related Compound; 6-Chloro-4-hydroxy-2-methyl-N-(5-(hydroxymethyl)thiazol-2-yl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide; Despyridinyl Hydroxymethylthiazolyl Lornoxicam; 1246818-50-7; UNII-9F8K7V3A0S
EINECS	Contact for details

Quality Control

Our n-Des(2-Pyridinyl)-n-(5-Hydroxymethyl-2-Thiazolyl) Lornoxicam is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets high-grade standards suitable for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your research specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.