Description

Cyclopropyl Pemoline-D5 is a deuterated analog of pemoline, a central nervous system stimulant, specifically labeled with five deuterium atoms. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring the highest accuracy and reliability in analytical measurements. It is primarily required by pharmaceutical research laboratories, contract research organizations (CROs), and forensic toxicology units for method development, pharmacokinetic studies, and drug metabolism research.

Application

• Primary use as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for the quantification of pemoline and related compounds.
• Critical component in pharmacokinetic and bioanalytical studies to determine drug concentration in biological matrices like plasma, serum, and urine.
• Facilitates drug metabolism and disposition (DMPK) research, aiding in the identification and quantification of metabolites.
• Supports forensic analysis and doping control for the accurate detection of stimulants in compliance with WADA and other regulatory guidelines.
• Enables method validation and quality control in pharmaceutical development and manufacturing processes.
• Used in academic and institutional research focusing on neuropharmacology and the mechanism of action of stimulant drugs.

Basic Information

Product Name	Cyclopropyl Pemoline-D5
CAS No.	1246817-86-6
Molecular Formula	C9H3D5N2O2
Molecular Weight	185.20 g/mol
Synonyms	2-Amino-5-phenyl-4(5H)-oxazolone-d5; 2-Imino-5-phenyl-4-oxazolidinone-d5; Pemoline-d5; 5-Phenyl-2,4-dihydro-4H-imidazol-4-one-d5; 5-Phenyl-2-imino-4-oxazolidinone-d5; Stimol-2-d5; Cylert-d5 (deuterated analog); (RS)-2-Imino-5-phenyl-4-oxazolidinone-d5
EINECS	Contact for details

Quality Control

Every batch of Cyclopropyl Pemoline-D5 is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, verified by advanced analytical techniques including NMR, HPLC, and Mass Spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and impurity profile is provided with each shipment to ensure compliance with your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.