Description

Desacetyl Triflusal-13C6 is a stable isotope-labeled analog of the active metabolite of the antiplatelet agent Triflusal, specifically labeled with six carbon-13 atoms. This compound is an essential reference standard and internal standard for the precise quantification and pharmacokinetic studies of Triflusal and its metabolites in biological matrices using advanced analytical techniques like LC-MS/MS. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities engaged in bioanalytical method development, drug metabolism studies, and clinical trial support.

Application

• Bioanalytical Method Development: Serves as a critical internal standard for the accurate and sensitive quantification of Triflusal and Desacetyl Triflusal in plasma, serum, and other biological samples via mass spectrometry.
• Pharmacokinetic (PK) and Pharmacodynamic (PD) Studies: Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical research.
• Drug Metabolism Research: Used to elucidate metabolic pathways and identify metabolites, supporting drug safety and efficacy evaluations.
• Clinical Trial Analysis: Ensures reliable data generation for regulatory submissions by minimizing analytical variability in sample analysis.
• Quality Control & Assurance: Acts as a certified reference material for calibrating instruments and validating analytical methods in GLP/GMP-compliant laboratories.
• Stable Isotope Dilution Assays: Provides the foundation for highly accurate assays that correct for sample preparation losses and ionization suppression in mass spectrometry.

Basic Information

Product Name	Desacetyl Triflusal-13C6
CAS No.	1246817-12-8
Molecular Formula	C1313C6H11F3O4
Molecular Weight	~329.2 (for 13C6 labeled form)
Synonyms	2-Acetoxy-4-(trifluoromethyl)benzoic Acid-13C6; (2-Acetyloxy-4-(trifluoromethyl)benzoic Acid)-13C6; Triflusal Metabolite-13C6; HTB-13C6; 4-Trifluoromethylsalicylic Acid Acetate-13C6; Desacetyl Triflusal (phenyl-13C6); GR 79236X Metabolite-13C6
EINECS	Contact for details

Quality Control

Every batch of Desacetyl Triflusal-13C6 is manufactured and analyzed under strict quality systems. We provide comprehensive analytical data to ensure identity, purity, and isotopic enrichment meet the exacting standards required for quantitative bioanalysis. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting results for assay (HPLC), isotopic purity, chemical purity, and residual solvent analysis. Our quality commitment supports compliance with GLP and GMP guidelines for reference standards.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Assay (HPLC)	≥98.0%
Isotopic Purity	≥99 atom % 13C
Chemical Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.