Description

Moxifloxacin Hydrochloride-13Cd3 is a stable isotope-labeled analog of the fourth-generation fluoroquinolone antibiotic, moxifloxacin hydrochloride, where three hydrogen atoms are replaced by deuterium (13C-labeled). This compound serves as a critical internal standard for the precise and accurate quantification of moxifloxacin in complex biological matrices using advanced analytical techniques like LC-MS/MS. It is an essential tool for pharmaceutical R&D, bioanalytical laboratories, and clinical research organizations focused on pharmacokinetic studies, drug metabolism research, and ensuring regulatory compliance in drug development. The product is supplied with high chemical and isotopic purity to guarantee reliable and reproducible analytical results.

Application

• Bioanalytical Method Development & Validation: Primary application as an internal standard for the quantification of moxifloxacin in plasma, serum, urine, and tissue homogenates via LC-MS/MS.
• Pharmacokinetic (PK) and Pharmacodynamic (PD) Studies: Enables accurate measurement of drug concentration-time profiles to determine absorption, distribution, metabolism, and excretion (ADME) parameters.
• Clinical Research & Therapeutic Drug Monitoring (TDM): Supports studies on drug efficacy, safety, and optimal dosing regimens in patient populations.
• Drug Metabolism and Disposition Research: Used in in vitro and in vivo studies to investigate metabolic pathways and identify potential drug-drug interactions.
• Pharmaceutical Quality Control: Can be utilized in impurity profiling and assay development for moxifloxacin-based drug products.
• Forensic and Anti-Doping Analysis: Aids in the sensitive and specific detection of moxifloxacin in forensic toxicology and sports doping control.

Basic Information

Product Name	Moxifloxacin Hydrochloride-13Cd3
CAS No.	1246816-75-0
Molecular Formula	C21H21D3FN3O4·HCl
Molecular Weight	437.90 g/mol (approx.)
Synonyms	1-Cyclopropyl-7-[(1S,6S)-2,8-diazabicyclo[4.3.0]non-8-yl]-6-fluoro-8-methoxy-4-oxo-1,4-dihydroquinoline-3-carboxylic acid-13Cd3 hydrochloride; Moxifloxacin-d3 HCl; Moxifloxacin (13C-labeled) hydrochloride; Bay 12-8039-d3 hydrochloride; Avelox-d3 HCl; 13C-Labeled Moxifloxacin Hydrochloride; Deuterated Moxifloxacin HCl
EINECS	Contact for details

Quality Control

Every batch of Moxifloxacin Hydrochloride-13Cd3 is manufactured and analyzed under strict quality management systems. We guarantee high chemical purity and specified isotopic enrichment to meet the exacting demands of quantitative mass spectrometry. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing results for key parameters including assay (HPLC), isotopic purity (NMR/MS), related substances, residual solvents, and appearance. Our quality commitment ensures data integrity for your most critical research and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled in a controlled environment to minimize exposure to atmospheric humidity. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 99.0 atom % 13C (by NMR/MS)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.