Description

Carbovir-13C,D2 is a stable isotope-labeled analog of the antiviral nucleoside carbovir, specifically labeled with carbon-13 and deuterium. This compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring the highest accuracy and reliability in analytical measurements. It is primarily required by pharmaceutical research and development laboratories, clinical diagnostic facilities, and contract research organizations (CROs) engaged in pharmacokinetic studies, drug metabolism research, and bioanalytical method development for antiviral agents.

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of carbovir and related compounds in complex biological matrices such as plasma, serum, and tissue homogenates.
• Drug Metabolism and Pharmacokinetics (DMPK): Used in absorption, distribution, metabolism, and excretion (ADME) studies to track and quantify the parent drug and its metabolites.
• Bioanalytical Method Development and Validation: Serves as a reference standard to establish selectivity, sensitivity, accuracy, and precision in analytical assays.
• Clinical Research: Enables accurate therapeutic drug monitoring and pharmacokinetic profiling in clinical trials for antiviral therapies.
• Pharmaceutical Quality Control: Can be utilized in impurity profiling and assay development for drug substance and product manufacturing.
• Isotope Dilution Mass Spectrometry (IDMS): Employed in high-precision analytical techniques for definitive measurement in reference materials.

Basic Information

Product Name	Carbovir-13C,D2
CAS No.	1246816-59-0
Molecular Formula	C913CH10D2N5O4
Molecular Weight	Contact for details
Synonyms	Carbovir-13C,d2; (1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]-2-cyclopentene-1-methanol-13C,d2; (-)-Carbovir-13C,d2; 9-[(1S,4R)-4-(Hydroxymethyl-13C,d2)-2-cyclopenten-1-yl]guanine; NSC 614846-13C,d2; Abacavir related compound L-13C,d2; Stable Isotope Labeled Carbovir
EINECS	Contact for details

Quality Control

Our Carbovir-13C,D2 is manufactured under strict quality systems to ensure exceptional isotopic and chemical purity for critical analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity by HPLC, and identity confirmation. We adhere to relevant industry standards for reference materials, and custom synthesis and purification to meet specific client specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label or COA. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccation and storage under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Enrichment	≥99 atom % 13C; ≥98 atom % D
Chemical Purity (HPLC)	≥95.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.