Description

Chlor Cyclizine-D4 Hydrochloride CAS NO 1246816-11-4 is a deuterated isotopologue of the classic antihistamine, chlorcyclizine hydrochloride, where four hydrogen atoms are replaced by deuterium. This stable isotope-labeled compound is essential for use as an internal standard in quantitative mass spectrometry, ensuring the highest accuracy and reliability in analytical data. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, forensic, and clinical diagnostics sectors, where precise measurement of chlorcyclizine is required for pharmacokinetic studies, metabolism research, and bioanalytical method development.

Application

• Internal Standard for LC-MS/MS and GC-MS analysis of chlorcyclizine.
• Quantitative bioanalysis in pharmacokinetic and pharmacodynamic studies.
• Metabolite identification and drug metabolism research.
• Forensic toxicology for the accurate quantification of chlorcyclizine in biological matrices.
• Pharmaceutical quality control and impurity profiling.
• Clinical research involving antihistamine monitoring.
• Method development and validation in analytical laboratories.
• Environmental fate studies of pharmaceutical compounds.

Basic Information

Product Name	Chlor Cyclizine-D4 Hydrochloride
CAS No.	1246816-11-4
Molecular Formula	C18H17D4ClN2•HCl
Molecular Weight	337.31 g/mol (for monoisotopic mass)
Synonyms	1-[(4-Chlorophenyl)(phenyl)methyl]-4-methylpiperazine-d4 dihydrochloride; Chlorcyclizine-d4 HCl; 1-(p-Chloro-α-phenylbenzyl)-4-methylpiperazine-d4 hydrochloride; NSC-14077-d4; Histachlorazine-d4; Perazil-d4; Diparalene-d4; Mantadil-d4
EINECS	Contact for details

Quality Control

Our Chlor Cyclizine-D4 Hydrochloride is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic enrichment, chemical purity by HPLC, and confirmation of structure. We ensure compliance with relevant standards for high-purity reference materials, supporting traceable and reproducible research outcomes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0% (chemical purity)
Isotopic Enrichment	≥98 atom % D
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.