Description

Dibromopropamidine-D6 Dihydrochloride is a deuterated isotopologue of the antimicrobial agent dibromopropamidine, specifically designed for use as an internal standard in quantitative analytical methods. This high-purity compound is critical for ensuring accuracy and reliability in mass spectrometry-based analyses, particularly in pharmacokinetic and metabolic studies. It is primarily utilized by pharmaceutical researchers, analytical laboratories, and contract research organizations (CROs) engaged in drug development and quality control.

Application

• Internal Standard for LC-MS/MS: Serves as a stable, non-interfering reference compound for the precise quantification of dibromopropamidine and its metabolites in complex biological matrices like plasma, serum, and urine.
• Pharmaceutical R&D: Enables accurate pharmacokinetic (PK) and pharmacodynamic (PD) studies during the development of antimicrobial and antiseptic formulations.
• Metabolite Identification: Used in mass spectrometry to track and identify deuterated vs. non-deuterated species in metabolism studies.
• Bioanalytical Method Validation: A key component in developing and validating robust, GLP-compliant analytical methods for regulatory submissions.
• Quality Control in Manufacturing: Supports impurity profiling and assay verification of active pharmaceutical ingredients (APIs) containing related compounds.

Basic Information

Product Name	Dibromopropamidine-D6 Dihydrochloride
CAS No.	1246815-43-9
Molecular Formula	C17H14D6Br2N4O•2HCl
Molecular Weight	Contact for details
Synonyms	1,3-Di(4-amidinophenoxy)propane-D6 Dihydrochloride; 4,4'-(Propane-1,3-diyldioxy)dibenzamidine-D6 Dihydrochloride; Dibromopropamidine-d6 Dihydrochloride; 1,3-Di(4-amidinophenoxy)propane-α,α,β,β,γ,γ-d6 Dihydrochloride; Deuterated Dibromopropamidine Dihydrochloride; Dibromopropamidine Isotopologue; Internal Standard for Dibromopropamidine
EINECS	Contact for details

Quality Control

Every batch of Dibromopropamidine-D6 Dihydrochloride is manufactured and analyzed under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic techniques, to ensure compliance with industry standards for isotopic purity and chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and analytical results is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (D6)	≥98.0 atom % D
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.