Description

n-(3-Isopropylamino-2-Hydroxypropyl) Pindolol-D14 is a deuterated isotopologue of a key pindolol derivative, specifically designed for use as an internal standard in analytical chemistry. This high-purity compound is essential for ensuring accuracy and reliability in quantitative mass spectrometry, eliminating variability and improving data integrity. It is primarily required by pharmaceutical research laboratories, contract research organizations (CROs), and analytical service providers engaged in method development, pharmacokinetic studies, and metabolite identification.

Application

• Internal Standard for LC-MS/MS: Critical for the precise quantification of pindolol and its metabolites in complex biological matrices such as plasma, serum, and urine.
• Pharmacokinetic and Bioanalytical Research: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) studies.
• Metabolite Profiling: Used as a reference compound in the identification and quantification of drug metabolites.
• Method Development and Validation: Serves as a stable, non-interfering standard to establish robust, reproducible analytical protocols.
• Quality Control in Pharmaceutical Manufacturing: Supports impurity profiling and ensures batch-to-batch consistency of active pharmaceutical ingredients (APIs).
• Forensic and Clinical Toxicology: Aids in the accurate measurement of drug concentrations for diagnostic and legal purposes.

Basic Information

Product Name	n-(3-Isopropylamino-2-Hydroxypropyl) Pindolol-D14
CAS No.	1246815-15-5
Molecular Formula	C₁₄H₁₄D₁₄N₂O₂
Molecular Weight	~262.4 g/mol (deuterated form)
Synonyms	Pindolol D14 derivative; Deuterated Pindolol Impurity/Intermediate; 1-(1H-Indol-4-yloxy)-3-[(1-methylethyl)amino]-2-propanol-D14 derivative; 4-[2-Hydroxy-3-[(1-methylethyl)amino]propoxy]-1H-indole-D14; (RS)-1-(Indol-4-yloxy)-3-(isopropylamino)-2-propanol-D14; Isopropylamino-hydroxypropyl Pindolol-D14; Deuterated Internal Standard for Pindolol
EINECS	Contact for details

Quality Control

Our deuterated standards are manufactured under strict quality control protocols to guarantee isotopic purity and chemical integrity, essential for trace-level analysis. Each batch is characterized using advanced techniques including NMR (¹H, ¹³C) and High-Resolution Mass Spectrometry (HRMS) to confirm deuteration level and identity. A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and analytical results is provided with every shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term stability, consider storage at 2-8°C. Keep the container sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98.0 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.