Description

6-Amino-5-Nitroso-2-Thiouracil-13C,15N is a stable isotope-labeled derivative of a key heterocyclic thiouracil scaffold, essential for advanced analytical and research applications. This compound provides a critical internal standard for mass spectrometry, enabling precise quantification and metabolic pathway tracing in complex biological matrices. It is primarily utilized by researchers and developers in pharmaceutical R&D, agrochemical studies, and academic institutions focused on isotope dilution analysis and mechanistic studies.

Application

• Internal Standard for LC-MS/MS: Serves as a critical quantitative reference standard in bioanalytical method development for pharmacokinetic and metabolomic studies.
• Pharmaceutical Research: Used in the synthesis and metabolic tracing of novel drug candidates, particularly those based on thiouracil or pyrimidine-like structures.
• Agrochemical Development: Applied in environmental fate studies and residue analysis of agrochemicals using stable isotope labeling techniques.
• Biochemical Tracers: Facilitates the study of nucleotide metabolism and related biochemical pathways in cellular systems.
• Academic Research: A valuable tool for universities and research institutes conducting fundamental research in medicinal chemistry and analytical method validation.

Basic Information

Product Name	6-Amino-5-Nitroso-2-Thiouracil-13C,15N
CAS No.	1246814-68-5
Molecular Formula	C313CH3N315NO2S
Molecular Weight	~174.12 g/mol (labeled)
Synonyms	6-Amino-5-nitroso-2-thiouracil-13C,15N; 2-Thiouracil-6-amine-5-nitroso-13C,15N; 5-Nitroso-6-amino-2-thiouracil-13C,15N; 6-Amino-5-nitroso-2-mercapto-4-pyrimidinol-13C,15N; ANTU-13C,15N (labeled); Stable Isotope Labeled 6-Amino-5-nitroso-2-thiouracil; [13C,15N]-6-Amino-5-nitroso-2-thiouracil
EINECS	Contact for details

Quality Control

Every batch of our 6-Amino-5-Nitroso-2-Thiouracil-13C,15N is produced and tested under strict quality management protocols. We guarantee high chemical and isotopic purity, with comprehensive testing including HPLC for chemical assay and MS for isotopic enrichment verification. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with customer specifications and industry standards for stable isotope-labeled compounds.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant use.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (13C)	≥ 99 atom %
Isotopic Enrichment (15N)	≥ 99 atom %
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.