Description

1,3-Dibromo-2-(Trifluoromethoxy)Benzene is a high-purity, multi-functional aromatic building block designed for advanced chemical synthesis. This compound matters for its unique combination of bromine substituents and a trifluoromethoxy group, offering versatile reactivity for cross-coupling and functionalization reactions. It is primarily needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials industries for developing novel active ingredients and performance chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Serves as a crucial precursor for creating advanced herbicides, fungicides, and insecticides with enhanced efficacy and environmental profiles.
• Ligand & Catalyst Development: Used in the design and synthesis of specialized ligands for transition metal catalysis and organocatalysts.
• Material Science Research: Employed in the synthesis of monomers for specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Acts as an electrophilic partner in Suzuki, Stille, and Negishi couplings to introduce complex aryl motifs.
• Fluorine Chemistry: The trifluoromethoxy group makes it valuable for studying structure-activity relationships (SAR) and metabolic stability in drug discovery.

Basic Information

Product Name	1,3-Dibromo-2-(Trifluoromethoxy)Benzene
CAS No.	1246643-52-6
Molecular Formula	C7H3Br2F3O
Molecular Weight	323.90 g/mol
Synonyms	2,6-Dibromo-1-(trifluoromethoxy)benzene; 1,3-Dibromo-2-(trifluoromethoxy)benzene; Benzene, 1,3-dibromo-2-(trifluoromethoxy)-; 2-(Trifluoromethoxy)-1,3-dibromobenzene; 1,3-Dibromo-2-trifluoromethoxybenzene; 2,6-Dibromophenyl trifluoromethyl ether
EINECS	Contact for details

Quality Control

Our 1,3-Dibromo-2-(Trifluoromethoxy)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. The container must be kept tightly sealed to prevent moisture ingress and potential decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.