Description

(5Z,8Z,11Z,14Z,17Z-Eicosapentaenoyl) Coenzyme A (Ammonium Salt) is a high-purity, chemically defined derivative of eicosapentaenoic acid (EPA) conjugated to coenzyme A, supplied as an ammonium salt for enhanced stability. This specialized biochemical is a critical research tool and a potential intermediate for synthesizing bioactive lipid mediators and studying lipid metabolism pathways. It is essential for researchers and developers in pharmaceutical discovery, biochemistry, and nutraceutical science who require precise, well-characterized substrates for enzymatic assays, metabolic studies, and the production of high-value lipid-based compounds.

Application

• Biochemical Research & Enzyme Assays: Serves as a specific substrate for studying the activity of acyl-CoA synthetases, acyltransferases, and other enzymes involved in the eicosanoid and specialized pro-resolving mediator (SPM) biosynthesis pathways.
• Pharmaceutical Development: Used as a key intermediate in the research and synthesis of novel anti-inflammatory lipid mediators, such as resolvins and protectins, derived from EPA.
• Metabolic Pathway Analysis: Enables detailed investigation of fatty acid oxidation, elongation, and complex lipid (e.g., phospholipid, triglyceride) biosynthesis in cellular and in vitro systems.
• Nutraceutical & Cosmetic Ingredient Research: Acts as a reference standard or a precursor in the development of advanced bioactive formulations targeting inflammation and cellular health.
• Diagnostic Kit Manufacturing: Employed in the production of calibration standards and reagents for clinical diagnostic kits measuring specific metabolic disorders or enzyme deficiencies.
• Academic & Institutional Research: Provides a critical tool for universities and research institutes exploring lipidomics, cell signaling, and the molecular mechanisms of diseases like metabolic syndrome and neurodegeneration.

Basic Information

Product Name	(5Z,8Z,11Z,14Z,17Z-Eicosapentaenoyl) Coenzyme A (Ammonium Salt)
CAS No.	1246522-05-3
Molecular Formula	C42H70N7O19P3S
Molecular Weight	1102.0 g/mol (approximate)
Synonyms	EPA-CoA (Ammonium Salt); Eicosapentaenoyl-CoA; 20:5(n-3)-CoA; all-cis-5,8,11,14,17-Eicosapentaenoyl Coenzyme A Ammonium Salt; Arachidonic Acid Analog-CoA; CoA-EPA; (5Z,8Z,11Z,14Z,17Z)-Icosapentaenoyl-CoA; (all-Z)-5,8,11,14,17-Eicosapentaenoylcoenzyme A
EINECS	Contact for details

Quality Control

Every batch of (5Z,8Z,11Z,14Z,17Z-Eicosapentaenoyl) Coenzyme A (Ammonium Salt) is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality assurance protocols are designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC), identity confirmation (by MS and/or NMR), and other critical parameters is provided with each shipment to guarantee traceability and reliability for your sensitive experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated under an inert atmosphere. Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.