Description

n-[11-(Dipyrrometheneboron Difluoride)Undecanoyl]-D-Erythro-Sphinganine is a high-purity, fluorescently labeled sphingolipid derivative, designed for advanced biochemical research and diagnostic applications. This compound matters as a critical tool for the sensitive detection and tracking of sphingolipid metabolism, membrane dynamics, and cellular signaling pathways. It is primarily needed by researchers and developers in the pharmaceutical, biotechnology, and life science sectors for use in fluorescence microscopy, flow cytometry, and as a probe in lipidomics studies.

Application

• Fluorescent Cell Labeling: Used as a vital stain for real-time visualization of lipid rafts, membrane trafficking, and intracellular lipid distribution via confocal or super-resolution microscopy.
• Flow Cytometry Analysis: Serves as a specific probe for quantifying sphingolipid content and metabolism in live cell populations.
• Lipidomics Research: Acts as an internal standard or a tagged substrate in mass spectrometry-based studies to investigate sphingolipid biosynthesis and degradation pathways.
• Drug Discovery Screening: Employed in high-throughput assays to identify and evaluate compounds that modulate enzymes involved in sphingolipid signaling, such as sphingomyelinases or ceramidases.
• Diagnostic Probe Development: Utilized in the design of fluorescent sensors and kits for detecting enzymatic activity or specific lipid biomarkers associated with disease states.

Basic Information

Product Name	n-[11-(Dipyrrometheneboron Difluoride)Undecanoyl]-D-Erythro-Sphinganine
CAS No.	1246355-59-8
Molecular Formula	C40H65BF2N4O3
Molecular Weight	698.78 g/mol
Synonyms	BODIPY FL C12-Sphinganine; BODIPY® FL C12-Sphinganine; N-[(11-{5-[(2E,4E)-5-[(1E)-1-{3,5-Dimethyl-1H-pyrrol-2-yl}ethylidene]-3,4-dimethyl-1H-pyrrol-2-ylidene]penta-2,4-dien-1-ylidene}-4,4-difluoro-4-bora-3a,4a-diaza-s-indacen-3-yl)undecanoyl]-D-erythro-sphinganine; Fluorescent Sphinganine Derivative; BODIPY-Labeled Sphingolipid; Sphinganine, N-[11-(dipyrrometheneboron difluoride)undecanoyl]-D-erythro-
EINECS	Contact for details

Quality Control

Our n-[11-(Dipyrrometheneboron Difluoride)Undecanoyl]-D-Erythro-Sphinganine is manufactured under strict quality systems to ensure batch-to-batch consistency and high performance for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity, mass spectrometry for identity confirmation, and fluorescence spectroscopy to validate photophysical properties. Certificates of Analysis (COA) detailing all specifications and test results are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. Allow the product to equilibrate to room temperature before opening to prevent condensation and moisture uptake. The storage area should be dry and well-ventilated.

Specification

Item	Specification
Appearance	Orange to red solid or film
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Extinction Coefficient (ε)	~90,000 cm-1M-1 (at λmax)
Fluorescence Emission	~515 nm
Solubility	Soluble in DMSO, DMF, ethanol; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.