Description

1,2-Diphytanoyl-Sn-Glycero-3-Phosphoethanolamine-n-(7-Nitro-2-1,3-Benzoxadiazol-4-Yl) (Ammonium Salt) is a high-purity, fluorescently labeled phospholipid derivative, essential for advanced membrane biophysics and cell biology research. Its core value lies in the unique combination of the stable, branched phytanoyl chains and the bright, photostable NBD fluorophore, which enables precise probing of lipid dynamics and membrane organization. This compound is critically needed by researchers in pharmaceutical development, academic institutions, and diagnostic kit manufacturers for applications such as lipid raft studies, membrane fusion assays, and fluorescence-based cellular imaging.

Application

• Membrane Biophysics Research: As a fluorescent lipid probe for studying lipid bilayer properties, phase separation, and the formation of lipid rafts in model membranes.
• Cell Biology & Imaging: For labeling and tracking cellular membranes, investigating endocytosis, exocytosis, and intracellular lipid trafficking using fluorescence microscopy (e.g., confocal, TIRF).
• Liposome & Drug Delivery System Development: Incorporation into liposomal formulations to monitor carrier stability, cellular uptake efficiency, and biodistribution in real-time.
• Protein-Lipid Interaction Studies: Used in fluorescence anisotropy or FRET-based assays to investigate the binding and activity of membrane-associated proteins and peptides.
• Diagnostic Assay Development: Serves as a key component in developing fluorescence-based diagnostic sensors and kits for detecting enzymatic activity or specific biomarkers.
• High-Throughput Screening (HTS): Employed in pharmaceutical screens to identify compounds that affect membrane permeability, lipid metabolism, or specific lipid-protein interactions.

Basic Information

Product Name	1,2-Diphytanoyl-Sn-Glycero-3-Phosphoethanolamine-n-(7-Nitro-2-1,3-Benzoxadiazol-4-Yl) (Ammonium Salt)
CAS No.	1246355-56-5
Molecular Formula	C73H124N4O12P
Molecular Weight	1281.78 g/mol
Synonyms	NBD-PE (Diphytanoyl); 1,2-Diphytanoyl-sn-glycero-3-phosphoethanolamine-N-(7-nitro-2-1,3-benzoxadiazol-4-yl); N-(7-Nitro-2,1,3-benzoxadiazol-4-yl)-1,2-diphytanoyl-sn-glycero-3-phosphoethanolamine; Fluorescent PE Lipid; NBD DPhyPE; NBD-labeled Diphytanoyl Phosphatidylethanolamine; Ammonium salt of NBD-DPhPE; NBD Phosphatidylethanolamine (branched chain)
EINECS	Contact for details

Quality Control

Our 1,2-Diphytanoyl-Sn-Glycero-3-Phosphoethanolamine-n-(7-Nitro-2-1,3-Benzoxadiazol-4-Yl) (Ammonium Salt) is manufactured under strict quality systems suitable for research and in-vitro diagnostic use. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure consistency and performance. A comprehensive Certificate of Analysis (COA) detailing purity, fluorescence properties, and absence of critical impurities is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, keep the primary container sealed in a secondary container with a desiccant. Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Yellow to orange solid or film
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Fluorescence Properties	Ex/Em ~460/535 nm in methanol
Solubility	Soluble in chloroform, methanol, DMSO
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.