Description

n-(2'-(S)-Hydroxyoleoyl)-D-Erythro-Sphingosine CAS NO 1246298-53-2 is a high-purity, synthetic sphingolipid derivative, specifically a hydroxylated ceramide analog. This compound is a critical biochemical tool and advanced intermediate for research into lipid signaling pathways, cellular membrane structure, and skin barrier function. It is essential for pharmaceutical R&D, advanced cosmetic formulation, and academic research focused on sphingolipid metabolism and ceramide biology.

Application

• Biochemical Research: A key reference standard and precursor for studying ceramide synthesis, metabolism, and their role in apoptosis and cell signaling.
• Pharmaceutical Development: Used as an intermediate in the synthesis of novel therapeutic agents targeting skin disorders, inflammatory pathways, and cancer.
• Advanced Cosmetic Science: Serves as a high-performance active ingredient or model compound in the development of premium skincare products aimed at restoring and enhancing the skin's natural lipid barrier.
• Lipidomics & Analytical Standards: Employed as a certified standard in mass spectrometry and chromatography for the accurate quantification and profiling of complex sphingolipids in biological samples.
• Cell Culture & In Vitro Studies: Used to modulate membrane properties and study the effects of specific ceramide species on cellular behavior in controlled experimental systems.

Basic Information

Product Name	n-(2'-(S)-Hydroxyoleoyl)-D-Erythro-Sphingosine
CAS No.	1246298-53-2
Molecular Formula	C36H69NO5
Molecular Weight	595.95 g/mol
Synonyms	(2S)-2-Hydroxy-N-[(2S,3R,4E)-1,3-dihydroxyoctadec-4-en-2-yl]octadec-9-enamide; (S)-2-Hydroxyoleoyl-D-erythro-sphingosine; N-((2S)-2-Hydroxyoleoyl)-D-erythro-sphingosine; Hydroxyoleoyl Ceramide; Ceramide analog with 2'-S-hydroxyoleoyl chain; D-erythro-Sphingosine, N-[(2S)-2-hydroxy-9-octadecenoyl]-; A sphingolipid research chemical.
EINECS	Contact for details

Quality Control

Every batch of n-(2'-(S)-Hydroxyoleoyl)-D-Erythro-Sphingosine is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality system is designed to meet the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity by HPLC, identity confirmation by NMR and MS, and other critical parameters is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.