Description

1-[3-Bromo-4-(2,2,2-Trifluoroethoxy)-Phenyl]-Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its distinct bromo- and trifluoroethoxy-substituted aromatic ketone structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting complex disease pathways. It is primarily needed by pharmaceutical R&D laboratories, agrochemical innovators, and specialty chemical manufacturers focused on fluorinated compounds.

Application

• Key building block in the synthesis of novel pharmaceutical candidates, especially those requiring halogen and fluorine motifs for enhanced bioactivity and metabolic stability.
• Intermediate for the development of agrochemicals, including herbicides and pesticides, where the trifluoroethoxy group can influence selectivity and environmental fate.
• Versatile precursor in organic synthesis for creating complex molecules used in material science and liquid crystal applications.
• Research chemical for structure-activity relationship (SAR) studies in drug discovery programs.
• Starting material for synthesizing fluorinated fine chemicals and specialty dyes.

Basic Information

Product Name	1-[3-Bromo-4-(2,2,2-Trifluoroethoxy)-Phenyl]-Ethanone
CAS No.	1246288-95-8
Molecular Formula	C10H8BrF3O2
Molecular Weight	297.07 g/mol
Synonyms	3'-Bromo-4'-(2,2,2-trifluoroethoxy)acetophenone; 1-[3-Bromo-4-(2,2,2-trifluoroethoxy)phenyl]ethan-1-one; 3-Bromo-4-(2,2,2-trifluoroethoxy)acetophenone; 4'-Trifluoroethoxy-3'-bromoacetophenone; 3-Bromo-4-trifluoroethoxyacetophenone; 1-(3-Bromo-4-(2,2,2-trifluoroethoxy)phenyl)ethanone; Ethanone, 1-[3-bromo-4-(2,2,2-trifluoroethoxy)phenyl]-
EINECS	Contact for details

Quality Control

Our 1-[3-Bromo-4-(2,2,2-Trifluoroethoxy)-Phenyl]-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports compliance with cGMP and ISO standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.