Description

Potassium Trifluoro(2-(Methylsulfonyl)Pyrimidin-5-Yl)Borate is a high-purity organoboron reagent, specifically a potassium trifluoroborate salt, designed for advanced synthetic applications. Its core value lies in its enhanced stability and reactivity profile compared to traditional boronic acids, making it a critical building block for precise carbon-carbon bond formation. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is primarily utilized in Suzuki-Miyaura cross-coupling reactions to construct complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing pyrimidine-based active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
• Agrochemical Research & Development: Used in the synthesis of novel herbicides, fungicides, and insecticides containing functionalized pyrimidine rings.
• Material Science Precursor: Serves as a specialized monomer or building block for creating organic electronic materials and metal-organic frameworks (MOFs).
• Chemical Biology & Probe Development: Employed in the synthesis of labeled compounds and molecular probes for biochemical assays and diagnostic applications.
• Process Chemistry & Scale-up: Valued for its improved handling characteristics and shelf-life in large-scale manufacturing processes for fine chemicals.

Basic Information

Item	Details
Product Name	Potassium Trifluoro(2-(Methylsulfonyl)Pyrimidin-5-Yl)Borate
CAS No.	1245906-71-1
Molecular Formula	C5H4BF3KN2O2S
Molecular Weight	255.07 g/mol
Synonyms	Potassium (2-(Methylsulfonyl)pyrimidin-5-yl)trifluoroborate; 2-(Methylsulfonyl)-5-pyrimidinyltrifluoroborate Potassium Salt; (2-Methanesulfonylpyrimidin-5-yl)trifluoroboronic Acid Potassium Salt; 5-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-2-(methylsulfonyl)pyrimidine (precursor); Potassium Trifluoro((2-(methylsulfonyl)pyrimidin-5-yl))borate; (2-Methylsulfonylpyrimidin-5-yl)trifluoroborate Potassium; Potassium (2-Methanesulfonylpyrimidin-5-yl)trifluoroboranuide
EINECS	Contact for details

Quality Control

Our Potassium Trifluoro(2-(Methylsulfonyl)Pyrimidin-5-Yl)Borate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (1H, 11B, 19F), HPLC for purity assessment, and KF titration for moisture content, to ensure compliance with exacting standards for research and commercial use. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. Due to its hygroscopic nature, the container should be kept sealed under an inert atmosphere (argon or nitrogen) when not in use to prevent moisture absorption and decomposition. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
11B NMR Purity	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.