Description

(S)-Benzyl 1-Chloropropan-2-Ylcarbamate CAS NO 1245643-24-6 is a chiral, non-natural amino acid derivative characterized by its benzyl-protected carbamate group and chloropropane side chain. This compound matters as a high-value, stereochemically pure building block essential for the synthesis of complex pharmaceutical intermediates and bioactive molecules. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for protease inhibitors and other targeted therapies.
• Peptidomimetics Synthesis: Used to incorporate non-natural amino acid residues into peptide chains to enhance stability, bioavailability, and biological activity.
• Agrochemical Research: Serves as a building block for creating chiral herbicides, fungicides, and plant growth regulators with improved efficacy and environmental profiles.
• Ligand and Catalyst Development: Employed in the preparation of chiral ligands for asymmetric catalysis and organometallic complexes.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring high enantiomeric purity and reliable chemical consistency.

Basic Information

Product Name	(S)-Benzyl 1-Chloropropan-2-Ylcarbamate
CAS No.	1245643-24-6
Molecular Formula	C11H14ClNO2
Molecular Weight	227.69 g/mol
Synonyms	(S)-Benzyl (1-chloropropan-2-yl)carbamate; (S)-1-Chloro-2-((benzyloxycarbonyl)amino)propane; Carbamic acid, N-(1-chloro-2-propanyl)-, phenylmethyl ester, (S)-; Z-(S)-1-Chloro-2-aminopropane; Cbz-(S)-1-Chloro-2-aminopropane; (S)-N-Cbz-1-Chloro-2-aminopropane; (S)-Benzyloxycarbonyl-1-chloro-2-aminopropane; (S)-1-Chloro-2-(N-benzyloxycarbonyl)aminopropane
EINECS	Contact for details

Quality Control

Our (S)-Benzyl 1-Chloropropan-2-Ylcarbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with high-purity standards for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.