Description

3-(3-Chloro-4-Ethoxyphenyl)-3-Oxopropanenitrile is a specialized organic intermediate featuring a β-ketonitrile functional group attached to a substituted phenyl ring. This compound matters for its role as a versatile building block in the synthesis of more complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on active pharmaceutical ingredients (APIs), crop protection agents, and advanced material precursors.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Serves as a building block for developing new herbicides, fungicides, and insecticides, leveraging the reactivity of the ketone and nitrile groups.
• Material Science Research: Used in the development of organic semiconductors, liquid crystals, and photoactive polymers due to its conjugated molecular structure.
• Chemical Research & Development: Employed in methodological studies for C-C bond formation and cyclization reactions, such as in the synthesis of heterocyclic compounds like pyrazoles and isoxazoles.
• Fine Chemical Production: Integral in custom synthesis projects for producing high-value, low-volume specialty chemicals for various industrial applications.

Basic Information

Product Name	3-(3-Chloro-4-Ethoxyphenyl)-3-Oxopropanenitrile
CAS No.	1243604-43-4
Molecular Formula	C11H10ClNO2
Molecular Weight	223.66 g/mol
Synonyms	3-Oxo-3-(3-chloro-4-ethoxyphenyl)propanenitrile; 3-(3-Chloro-4-ethoxyphenyl)-3-oxopropionitrile; 2-(3-Chloro-4-ethoxyphenyl)acetyl cyanide; 3-Chloro-4-ethoxybenzoylacetonitrile; β-Oxo-3-chloro-4-ethoxybenzenepropanenitrile; 1-(3-Chloro-4-ethoxyphenyl)-2-cyanoethan-1-one; 3-Chloro-4-ethoxy-β-oxobenzenepropanenitrile
EINECS	Contact for details

Quality Control

Our 3-(3-Chloro-4-Ethoxyphenyl)-3-Oxopropanenitrile is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates and other relevant industry standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive; therefore, containers should be amber or opaque. Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.