Description

3-Bromo-2-Cyanobenzyl Bromide is a versatile and highly reactive bifunctional aromatic building block, essential for constructing complex molecular architectures. Its dual reactive sites, the bromine and cyanobenzyl bromide groups, make it a critical intermediate for introducing specific functional handles in advanced synthesis. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, ligand synthesis, and material science.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly in kinase inhibitor and CNS-targeted therapeutic research.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging its aromatic core for bioactive molecule construction.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Monomer: Employed in the research and development of advanced polymers and functional organic materials with specific electronic or photophysical properties.
• Chemical Biology Probes: Useful for creating molecular probes and tags for studying biological processes and protein interactions.
• Cross-Coupling Reactions: An excellent substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form biaryl and other complex structures.

Basic Information

Product Name	3-Bromo-2-Cyanobenzyl Bromide
CAS No.	1243536-87-9
Molecular Formula	C8H5Br2N
Molecular Weight	275.94 g/mol
Synonyms	2-(Bromomethyl)-6-bromobenzonitrile; 6-Bromo-2-(bromomethyl)benzonitrile; 2-Cyano-3,6-dibromotoluene; alpha,3-Dibromo-2-cyanotoluene; 1-Bromo-2-(bromomethyl)-3-cyanobenzene; 3-Bromo-2-(bromomethyl)benzonitrile; Benzene, 1-bromo-2-(bromomethyl)-3-cyano-; (3-Bromo-2-cyanophenyl)methyl bromide
EINECS	Contact for details

Quality Control

Our 3-Bromo-2-Cyanobenzyl Bromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic and spectroscopic data (HPLC, GC, NMR) are provided to guarantee traceability and specification compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.