Description

1-Cyclopropoxy-2-Fluoro-Benzene is a specialized fluorinated aromatic ether building block of significant interest in advanced organic synthesis. Its molecular structure, featuring a cyclopropyl ether linkage adjacent to a fluorine atom, makes it a valuable precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) and anti-inflammatory therapies.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides, leveraging the metabolic stability imparted by the cyclopropoxy group.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for transition metal catalysis and organocatalysts due to its unique steric and electronic profile.
• Material Science Precursor: Employed in the synthesis of monomers or functional agents for advanced polymers and liquid crystalline materials.
• Chemical Biology Probe Synthesis: Utilized to create fluorinated analogs of bioactive molecules for structure-activity relationship (SAR) studies and mechanistic investigations.

Basic Information

Product Name	1-Cyclopropoxy-2-Fluoro-Benzene
CAS No.	1243459-26-8
Molecular Formula	C9H9FO
Molecular Weight	152.17 g/mol
Synonyms	2-Fluoro-1-cyclopropoxybenzene; o-Fluorophenyl cyclopropyl ether; 1-Fluoro-2-cyclopropoxybenzene; Cyclopropyl 2-fluorophenyl ether; Benzene, 1-cyclopropoxy-2-fluoro-; 2-Fluorophenyl cyclopropyl ether
EINECS	Contact for details

Quality Control

Our 1-Cyclopropoxy-2-Fluoro-Benzene is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and process chemistry. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider maintaining under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.