Description

4-Hydroxy-2-Iodobenzonitrile is a versatile iodinated aromatic nitrile derivative, serving as a key synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a phenolic hydroxyl group and an ortho-positioned iodine atom, makes it a valuable precursor for constructing complex molecules through cross-coupling and functional group transformations. This compound is primarily utilized by research institutions and pharmaceutical R&D teams engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing potential drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and organic synthesis.
• Material Science Research: Employed in the synthesis of advanced organic materials, including liquid crystals and organic semiconductors.
• Chemical Biology Probes: Useful for creating labeled compounds and molecular probes for biochemical and diagnostic research.
• Academic & Industrial R&D: A valuable reagent for method development and exploratory synthesis in university and corporate research laboratories.

Basic Information

Product Name	4-Hydroxy-2-Iodobenzonitrile
CAS No.	1243386-89-1
Molecular Formula	C7H4INO
Molecular Weight	244.02 g/mol
Synonyms	2-Iodo-4-hydroxybenzonitrile; 4-Hydroxy-2-iodobenzonitrile; 2-Cyano-5-iodophenol; 5-Iodo-2-hydroxybenzonitrile; Benzonitrile, 4-hydroxy-2-iodo-; 4-Hydroxy-2-iodobenzene carbonitrile; 2-Iodo-4-hydroxybenzenecarbonitrile; 5-Iodosalicylonitrile
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-2-Iodobenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to reliable supply and batch-to-batch consistency supports your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.