Description

2-(2-Methoxyphenyl)-1-Methyl-3-(Diphenylphosphino)-1H-Indole is a specialized, high-value organophosphorus ligand used in advanced catalytic processes. Its unique indole-based, phosphine-substituted structure makes it a critical component for enabling highly selective and efficient cross-coupling reactions in fine chemical synthesis. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise control over reaction pathways to create complex molecules.

Application

• Homogeneous Catalysis: As a sophisticated ligand for palladium, nickel, and other transition metal catalysts in cross-coupling reactions (e.g., Suzuki-Miyaura, Heck, Buchwald-Hartwig).
• Pharmaceutical Intermediates: Synthesis of complex, nitrogen-containing heterocyclic compounds for active pharmaceutical ingredients (APIs).
• Agrochemical Research: Development of novel pesticides and herbicides requiring selective bond formation.
• Material Science: Facilitating the synthesis of organic electronic materials and functional polymers.
• Asymmetric Synthesis: Potential use in creating chiral catalysts for enantioselective transformations.
• Academic & Industrial R&D: A valuable tool for methodology development and exploring new catalytic systems in laboratory settings.

Basic Information

Product Name	2-(2-Methoxyphenyl)-1-Methyl-3-(Diphenylphosphino)-1H-Indole
CAS No.	1242759-01-8
Molecular Formula	C28H24NOP
Molecular Weight	413.47 g/mol
Synonyms	1-Methyl-2-(2-methoxyphenyl)-3-(diphenylphosphino)-1H-indole; 3-(Diphenylphosphino)-1-methyl-2-(2-methoxyphenyl)-1H-indole; 2-(2-Methoxyphenyl)-1-methyl-3-(diphenylphosphino)indole; P,N-Ligand; Indole-based phosphine ligand; Methoxy-substituted indolylphosphine
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Methoxyphenyl)-1-Methyl-3-(Diphenylphosphino)-1H-Indole is manufactured and tested under strict quality management protocols to ensure consistency and reliability for sensitive catalytic applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated place. Due to its sensitivity to oxidation, the container should only be opened in an inert environment and resealed immediately after use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.