Description

2-T-Butyl-3-Hydroxy-5-(Trifluoromethyl)Isoindolin-1-One is a specialized heterocyclic compound featuring a trifluoromethyl group, which imparts unique physicochemical properties critical for advanced material and pharmaceutical synthesis. This compound serves as a high-value building block or intermediate in the development of complex molecules, offering significant advantages in tuning lipophilicity, metabolic stability, and binding affinity. It is primarily sought by R&D and production teams in the pharmaceutical, agrochemical, and advanced material science sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring enhanced bioavailability.
• Agrochemical Active Ingredient Synthesis: Used in the research and development of next-generation herbicides, fungicides, or insecticides where the trifluoromethyl group enhances biological activity.
• Advanced Material Precursor: Serves as a monomer or functional additive in the production of specialty polymers, liquid crystals, or organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial labs for method development, catalysis studies, and exploring new chemical spaces in medicinal chemistry.
• Fluorine Chemistry Studies: A valuable substrate for investigating the effects of fluorine substitution on reaction pathways and molecular properties.

Basic Information

Product Name	2-T-Butyl-3-Hydroxy-5-(Trifluoromethyl)Isoindolin-1-One
CAS No.	1242336-73-7
Molecular Formula	C₁₃H₁₄F₃NO₂
Molecular Weight	273.25 g/mol
Synonyms	2-tert-Butyl-3-hydroxy-5-(trifluoromethyl)isoindolin-1-one; 2-(tert-Butyl)-3-hydroxy-5-(trifluoromethyl)-1H-isoindol-1-one; 5-(Trifluoromethyl)-2-tert-butyl-3-hydroxyisoindolin-1-one; 1242336-73-7; 2-Tert-butyl-3-hydroxy-5-trifluoromethylisoindolin-1-one
EINECS	Contact for details

Quality Control

Every batch of 2-T-Butyl-3-Hydroxy-5-(Trifluoromethyl)Isoindolin-1-One is manufactured under strict quality management systems. Our products undergo rigorous quality testing including HPLC, NMR, and MS to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request. We are committed to meeting the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.