Description

2-T-Butyl-3-Hydroxy-4-Trifluoromethylisoindolin-1-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique isoindolinone core functionalized with a trifluoromethyl group. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting complex disease pathways. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing next-generation therapeutics and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the biological activity of the trifluoromethyl and isoindolinone motifs.
• Organic Synthesis: Serves as a versatile precursor for constructing complex heterocyclic compounds in medicinal chemistry and material science.
• Chemical Reference Standard: Employed as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	2-T-Butyl-3-Hydroxy-4-Trifluoromethylisoindolin-1-One
CAS No.	1242336-58-8
Molecular Formula	C₁₃H₁₄F₃NO₂
Molecular Weight	273.25 g/mol
Synonyms	2-tert-Butyl-3-hydroxy-4-(trifluoromethyl)isoindolin-1-one; 2-(tert-Butyl)-3-hydroxy-4-(trifluoromethyl)-1H-isoindol-1-one; 2-tert-Butyl-3-hydroxy-4-trifluoromethyl-1-isoindolinone; 1242336-58-8; 2-T-Butyl-3-Hydroxy-4-Trifluoromethyl-1-Isoindolinone; 2-(1,1-Dimethylethyl)-3-hydroxy-4-(trifluoromethyl)-1H-isoindol-1-one
EINECS	Contact for details

Quality Control

Our 2-T-Butyl-3-Hydroxy-4-Trifluoromethylisoindolin-1-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediate use. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.