Description

Oseltamivir-13C2-D3 is a stable isotope-labeled analog of the antiviral drug Oseltamivir Phosphate, specifically enriched with carbon-13 and deuterium. This compound is an essential reference standard and internal standard for the precise quantification and pharmacokinetic study of Oseltamivir in biological matrices using advanced analytical techniques like LC-MS/MS. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and analytical testing facilities engaged in drug metabolism and bioanalytical method development.

Application

• As a certified internal standard for the accurate quantification of Oseltamivir and its metabolites in bioanalytical assays (plasma, serum, urine).
• For use in pharmacokinetic (PK) and drug metabolism studies to understand the absorption, distribution, metabolism, and excretion (ADME) profile of Oseltamivir.
• In the development and validation of LC-MS/MS methods for therapeutic drug monitoring (TDM) and clinical research.
• As a critical reference material in quality control laboratories to ensure the accuracy and precision of analytical results.
• For research into drug-drug interactions and metabolic pathways involving neuraminidase inhibitors.

Basic Information

Product Name	Oseltamivir-13C2-D3
CAS No.	1242184-43-5
Molecular Formula	C16H25D313C2N2O4
Molecular Weight	Contact for details
Synonyms	Oseltamivir-13C2-D3; (3R,4R,5S)-4-Acetamido-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylic acid-13C2-D3 ethyl ester; Tamiflu-13C2-D3; GS 4104-13C2-D3; Ethyl (3R,4R,5S)-4-(acetylamino)-5-amino-3-(1-ethylpropoxy)-1-cyclohexene-1-carboxylate-13C2-D3; Oseltamivir Carboxylate-13C2-D3 precursor; Stable Isotope Labeled Oseltamivir
EINECS	Contact for details

Quality Control

Our Oseltamivir-13C2-D3 is manufactured under strict quality systems to ensure the highest isotopic and chemical purity required for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing isotopic enrichment (D and 13C), chemical purity by HPLC, and identity confirmation by NMR and MS. We adhere to relevant GMP guidelines for reference standards, ensuring traceability and reliability for your critical research and regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as indicated on the label. This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity (13C)	≥99 atom % 13C
Isotopic Purity (D)	≥98 atom % D
Chemical Purity (HPLC)	≥95.0%
Residual Solvents (GC)	Complies with ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.