Description

1-Bromo-2-Fluoro-4-Propoxybenzene is a high-purity fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound is valued for its unique substitution pattern, which allows for selective functionalization and the introduction of both bromine and fluorine atoms into complex molecular architectures. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic cores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the fluorine atom enhances biological activity and metabolic stability.
• Liquid Crystal & OLED Materials: Serves as a precursor in the production of specialty chemicals for electronic displays and organic light-emitting diodes (OLEDs).
• Cross-Coupling Reactions: The bromine substituent makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Functional Material Research: Employed in academic and industrial R&D for creating novel polymers, ligands, and advanced organic frameworks.
• Chemical Reference Standard: Used as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	1-Bromo-2-Fluoro-4-Propoxybenzene
CAS No.	1242070-96-7
Molecular Formula	C9H10BrFO
Molecular Weight	233.08 g/mol
Synonyms	2-Fluoro-4-propoxybromobenzene; 4-Bromo-3-fluoro-1-propoxybenzene; 1-Propoxy-2-fluoro-4-bromobenzene; Benzene, 1-bromo-2-fluoro-4-propoxy-; 2-Fluoro-1-bromo-4-propoxybenzene; 4-Propoxy-2-fluorobromobenzene
EINECS	Contact for details

Quality Control

Our 1-Bromo-2-Fluoro-4-Propoxybenzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for advanced intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.