Description

Methyl 2-(2-Fluoro-5-Nitrophenyl)Acetate is a high-purity fluorinated aromatic ester building block, essential for advanced organic synthesis. Its molecular structure, featuring both a nitro and a fluorine substituent, makes it a versatile intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of fluorinated drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides and pesticides, where the fluorine atom enhances biological activity and environmental stability.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of specialty polymers and advanced organic electronic materials.
• Ligand and Catalyst Development: Employed to synthesize novel chelating ligands for metal catalysts used in asymmetric synthesis and cross-coupling reactions.
• Fluorescent Probe Synthesis: Acts as a building block for developing nitroaromatic-based fluorescent dyes and molecular sensors.
• Academic & Contract Research: A critical reagent for methodological studies in organic chemistry, including novel fluorination and functional group transformation protocols.

Basic Information

Item	Detail
Product Name	Methyl 2-(2-Fluoro-5-Nitrophenyl)Acetate
CAS No.	1241920-02-4
Molecular Formula	C9H8FNO4
Molecular Weight	213.16 g/mol
Synonyms	Methyl (2-fluoro-5-nitrophenyl)acetate; 2-Fluoro-5-nitrophenylacetic acid methyl ester; Methyl 2-(2-fluoro-5-nitrophenyl)ethanoate; (2-Fluoro-5-nitrophenyl)acetic acid methyl ester; Methyl α-(2-fluoro-5-nitrophenyl)acetate; Methyl (2-fluoro-5-nitrobenzene)acetate; Acetic acid, (2-fluoro-5-nitrophenyl)-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 2-(2-Fluoro-5-Nitrophenyl)Acetate adheres to stringent in-process controls to ensure batch-to-batch consistency and high purity. Every lot is fully characterized and tested against rigorous internal specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to minimize degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.