Description

(2S)-2-(2,3,4,6-Tetrafluorophenyl)Pyrrolidine is a high-purity, chiral pyrrolidine derivative distinguished by its tetrafluorophenyl substituent, serving as a critical building block in advanced organic synthesis. Its value lies in providing a structurally defined, fluorinated chiral scaffold essential for modulating the physicochemical and pharmacokinetic properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients, particularly where fluorine substitution is strategically employed.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and insecticides where the fluorinated aromatic system enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis, enabling the production of enantiomerically pure compounds.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced organic materials that require fluorinated aromatic components for specific electronic or surface properties.
• Chemical Biology Probes: Utilized as a building block for fluorinated molecular probes and tags in biochemical and diagnostic research.

Basic Information

Product Name	(2S)-2-(2,3,4,6-Tetrafluorophenyl)Pyrrolidine
CAS No.	1241681-70-8
Molecular Formula	C10H9F4N
Molecular Weight	219.18 g/mol
Synonyms	(S)-2-(2,3,4,6-Tetrafluorophenyl)pyrrolidine; (2S)-2-(2,3,4,6-Tetrafluorophenyl)-1-azacyclopentane; Pyrrolidine, 2-(2,3,4,6-tetrafluorophenyl)-, (2S)-; (S)-2-(Perfluorophenyl)pyrrolidine (context-specific); 2-(2,3,4,6-Tetrafluorophenyl)-(S)-pyrrolidine; (S)-Tetrafluorophenylpyrrolidine; 1241681-70-8; (S)-2-(2,3,4,6-Tetrafluorophenyl)azacyclopentane
EINECS	Contact for details

Quality Control

Our (2S)-2-(2,3,4,6-Tetrafluorophenyl)Pyrrolidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for research and process development. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.