Description

3-Chloro-5-(Pentafluorosulfur)Phenylaceticacid is a high-value, fluorinated aromatic building block of significant interest in advanced organic synthesis. This compound matters for its unique molecular architecture, combining a phenylacetic acid core with chloro and pentafluorosulfur substituents, which imparts distinct electronic and steric properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients, particularly where enhanced metabolic stability and lipophilicity are desired targets.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in areas targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and fungicides, where the pentafluorosulfur group can contribute to improved biological activity and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for sophisticated ligands in transition metal catalysis, enabling novel synthetic transformations.
• Material Science Research: Employed in the synthesis of specialty polymers and liquid crystals, where fluorinated aromatic units modify material properties.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags or activity-based probes to study biological processes.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses serving the fine chemical and life science sectors.

Basic Information

Product Name	3-Chloro-5-(Pentafluorosulfur)Phenylaceticacid
CAS No.	1240257-26-4
Molecular Formula	C8H4ClF5O2S
Molecular Weight	294.63 g/mol
Synonyms	2-[3-Chloro-5-(pentafluoro-λ6-sulfanyl)phenyl]acetic acid; (3-Chloro-5-(pentafluorosulfanyl)phenyl)acetic acid; 3-Chloro-5-(SF5)Phenylacetic Acid; 3-Chloro-5-pentafluorosulfanylphenylacetic acid; 1240257-26-4; Acetic acid, 2-[3-chloro-5-(pentafluoro-λ6-sulfanyl)phenyl]-; 2-(3-Chloro-5-(pentafluorosulfanyl)phenyl)acetic acid
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-5-(Pentafluorosulfur)Phenylaceticacid is manufactured and analyzed under strict quality management protocols. We provide comprehensive analytical data to ensure consistency and purity for your critical research and development projects. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available for all shipments. Our quality systems are designed to support development from preclinical stages through to scale-up.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.