Description

2-Fluoro-4-(Trifluoromethoxy)Phenylacetic Acid, 97% is a high-purity fluorinated aromatic building block essential for advanced organic synthesis. This compound is valued for its unique trifluoromethoxy and fluorine substituents, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, contributing to improved performance and stability.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty polymers with enhanced chemical resistance, thermal stability, and unique surface properties.
• Chemical Research & Development: Employed in academic and industrial labs for method development, catalysis studies, and exploring new reactions involving fluorinated arenes.
• Fluorine-18 Radiochemistry: Potential use as a precursor or labeling scaffold in the synthesis of Positron Emission Tomography (PET) tracers for medical imaging.

Basic Information

Product Name	2-Fluoro-4-(Trifluoromethoxy)Phenylacetic Acid, 97%
CAS No.	1240256-95-4
Molecular Formula	C9H6F4O3
Molecular Weight	238.14 g/mol
Synonyms	[2-Fluoro-4-(trifluoromethoxy)phenyl]acetic acid; 2-(2-Fluoro-4-(trifluoromethoxy)phenyl)acetic Acid; α-(2-Fluoro-4-(trifluoromethoxy)phenyl)acetic Acid; 4-(Trifluoromethoxy)-2-fluorophenylacetic Acid; 2-Fluoro-4-trifluoromethoxyphenylacetic Acid; F-TFM-PAA; 1240256-95-4 (CAS)
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-(Trifluoromethoxy)Phenylacetic Acid is manufactured under strict quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure the specified purity of 97% (min.) and confirm identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and consistent quality for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if possible to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	97% min.
Water Content (KF)	< 0.5%
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.