Description

2-(Difluoromethoxy)-5-Fluorobenzamide, 97% is a high-purity fluorinated benzamide derivative, a key building block in advanced organic synthesis. Its value lies in its precise molecular structure, which is critical for introducing specific fluorinated motifs into target molecules, thereby influencing their biological activity and metabolic stability. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel active pharmaceutical ingredients (APIs), especially in drug discovery programs targeting central nervous system (CNS) disorders, oncology, and anti-infectives.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluoromethoxy and fluoro substituents can enhance bioavailability and environmental stability.
• Material Science Precursor: Serves as a specialty monomer or precursor for synthesizing advanced polymers and liquid crystals with unique optical and electronic properties.
• Chemical Biology Probe: Employed in medicinal chemistry to create molecular probes for studying enzyme mechanisms and receptor-ligand interactions due to its fluorine atoms, which are useful in 19F NMR spectroscopy.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-(Difluoromethoxy)-5-Fluorobenzamide, 97%
CAS No.	1240256-77-2
Molecular Formula	C8H6F3NO2
Molecular Weight	217.14 g/mol
Synonyms	5-Fluoro-2-(difluoromethoxy)benzamide; 2-(Difluoromethoxy)-5-fluorobenzoic acid amide; Benzamide, 2-(difluoromethoxy)-5-fluoro-; 1240256-77-2; 5-Fluoro-2-difluoromethoxybenzamide
EINECS	Contact for details

Quality Control

Every batch of 2-(Difluoromethoxy)-5-Fluorobenzamide is manufactured under strict quality management protocols. The product undergoes rigorous analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure it meets the specified 97% minimum purity. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.