Description

3-Chloro-2-Iodobenzonitrile (CAS NO 1239493-20-9) is a versatile halogenated benzonitrile derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and iodo substituents on the aromatic ring, makes it a valuable precursor for constructing complex molecules via cross-coupling reactions. This high-purity intermediate is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system disorders and oncology.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers and liquid crystals.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Sonogashira coupling reactions to form biaryl and other complex structures.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for transition metal catalysis.
• Chemical Biology Probes: Acts as a starting material for synthesizing molecular probes and tags used in biochemical assays.

Basic Information

Product Name	3-Chloro-2-Iodobenzonitrile
CAS No.	1239493-20-9
Molecular Formula	C7H3ClIN
Molecular Weight	263.46 g/mol
Synonyms	2-Iodo-3-chlorobenzonitrile; 3-Chloro-2-iodobenzene carbonitrile; Benzonitrile, 3-chloro-2-iodo-; 2-Cyano-6-chloroiodobenzene; 3-Chloro-2-iodophenyl cyanide; 1239493-20-9; 3-Chloro-2-iodo-benzonitrile
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Iodobenzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specification results. Our production adheres to cGMP principles where applicable, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and reducing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	< 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.