Description

5-Amino-2-Fluoro-Benzeneacetic Acid Ethyl Ester Hcl is a high-purity, protected amino acid derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing fluorinated aromatic systems and amino acid motifs.
• Peptidomimetic Research: Used in medicinal chemistry for the design and synthesis of peptide analogs and enzyme inhibitors.
• Agrochemical Synthesis: Building block for developing novel herbicides, fungicides, and plant growth regulators that benefit from the fluorine atom's metabolic stability.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Useful for creating fluorescent tags, affinity labels, and other molecular probes for biological target identification.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific chiral or fluorinated intermediates.

Basic Information

Product Name	5-Amino-2-Fluoro-Benzeneacetic Acid Ethyl Ester Hcl
CAS No.	1239460-72-0
Molecular Formula	C10H13FNO2·HCl
Molecular Weight	233.67 (Free base) / 270.13 (HCl salt)
Synonyms	Ethyl 2-(5-Amino-2-fluorophenyl)acetate hydrochloride; 2-(5-Amino-2-fluorophenyl)acetic Acid Ethyl Ester Hydrochloride; 5-Amino-2-fluorobenzeneacetic Acid Ethyl Ester Hydrochloride; 2-Fluoro-5-aminophenylacetic Acid Ethyl Ester HCl; Ethyl (5-Amino-2-fluorophenyl)acetate Hydrochloride; 5-Amino-2-fluoro-α-toluic Acid Ethyl Ester Hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Amino-2-Fluoro-Benzeneacetic Acid Ethyl Ester Hcl is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles. Our quality system is designed to support cGMP compliance for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.