Description

D-Serine, o-Cyclohexyl-n-[(1,1-Dimethylethoxy)Carbonyl]- is a protected derivative of the non-essential amino acid D-serine, featuring a tert-butoxycarbonyl (Boc) protecting group on the amine and an o-cyclohexyl modification. This compound is a critical chiral building block in advanced organic synthesis, enabling the controlled construction of complex peptides and other bioactive molecules. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams for developing novel therapeutics and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for neurological and metabolic targets.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate D-serine residues with orthogonal protection strategies.
• Proteomics Research: Serves as a modified amino acid standard or building block in the study of protein structure, function, and peptide mimetics.
• Chemical Biology Probes: Employed in the design and synthesis of labeled or tagged compounds for investigating biological pathways and enzyme mechanisms.
• Asymmetric Catalysis: May be used as a precursor or ligand in the development of chiral catalysts for enantioselective transformations.
• Academic & Industrial R&D: A valuable reagent for universities and contract research organizations (CROs) exploring novel synthetic methodologies and bioactive compounds.

Basic Information

Product Name	D-Serine, o-Cyclohexyl-n-[(1,1-Dimethylethoxy)Carbonyl]-
CAS No.	1239355-78-2
Molecular Formula	C14H25NO5
Molecular Weight	287.35 g/mol
Synonyms	(2R)-2-[[(2-Methylpropan-2-yl)oxycarbonyl]amino]-3-(2-cyclohexyloxy)propanoic acid; Boc-D-Ser(O-cyclohexyl)-OH; N-Boc-O-cyclohexyl-D-serine; tert-Butyl (R)-2-amino-3-(cyclohexyloxy)propanoate derivative; D-Serine, N-(tert-butoxycarbonyl)-O-cyclohexyl-; Boc-Ser(OcHex)-OH (D-isomer); N-(tert-Butoxycarbonyl)-O-cyclohexyl-D-serine
EINECS	Contact for details

Quality Control

Our D-Serine derivative is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% de
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.