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5-(3,4-Dihydro-5,7-Dihydroxy-4-Oxo-2H-1-Benzopyran-2-Yl)-2-Methoxyphenyl β-D-Glucopyranosiduronic Acid CAS NO 1237479-05-8


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CAS No.:1237479-05-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

5-(3,4-Dihydro-5,7-Dihydroxy-4-Oxo-2H-1-Benzopyran-2-Yl)-2-Methoxyphenyl β-D-Glucopyranosiduronic Acid is a high-purity, complex flavonoid-derived compound of significant interest in advanced research and development. This specialized chemical serves as a critical intermediate or reference standard for investigating metabolic pathways, bioavailability, and the biological activity of flavonoid conjugates. It is essential for pharmaceutical R&D laboratories, nutraceutical formulators, and academic institutions focused on natural product chemistry and pharmacokinetic studies.

Application

  • Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantification and identification of flavonoid metabolites in drug development and bioanalytical studies.
  • Metabolite Research: A key compound for studying the Phase II metabolism (glucuronidation) of flavonoid-based drug candidates and natural products.
  • Nutraceutical Analysis: Employed in the quality control and standardization of complex botanical extracts, ensuring accurate profiling of active conjugated components.
  • Biochemical Assay Development: Serves as a substrate or inhibitor in enzymatic assays targeting glucuronosyltransferases or other metabolic enzymes.
  • Academic Research: Facilitates fundamental research in pharmacology, toxicology, and natural product chemistry focused on flavonoid bioavailability and activity.
  • Analytical Method Development: Used to validate and calibrate advanced analytical techniques such as LC-MS/MS and HPLC for sensitive detection of conjugated phenolics.

Basic Information

Product Name 5-(3,4-Dihydro-5,7-Dihydroxy-4-Oxo-2H-1-Benzopyran-2-Yl)-2-Methoxyphenyl β-D-Glucopyranosiduronic Acid
CAS No. 1237479-05-8
Molecular Formula C22H22O13
Molecular Weight 494.40 g/mol
Synonyms 2-Methoxyphenyl 5,7-dihydroxy-4-oxo-3,4-dihydro-2H-1-benzopyran-2-yl β-D-Glucopyranosiduronic Acid; Flavonoid Glucuronide Metabolite; 5,7-Dihydroxy-4-oxoflavan-2-yl Glucuronide; 2'-Methoxyflavonoid Glucuronide; (2-Methoxyphenyl) 2-(5,7-dihydroxy-4-oxochroman-2-yl) β-D-Glucopyranosiduronic Acid; Conjugated Flavonoid Standard; Contact for additional synonyms.
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Quality Control

Our 5-(3,4-Dihydro-5,7-Dihydroxy-4-Oxo-2H-1-Benzopyran-2-Yl)-2-Methoxyphenyl β-D-Glucopyranosiduronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity confirmation and structural verification by spectroscopic methods (NMR, MS). Certificates of Analysis (COA) detailing batch-specific results are provided to ensure traceability and compliance with your research or quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a desiccated environment away from direct light exposure to maintain stability and purity.

Specification

Item Specification
Appearance White to off-white powder
Identification (IR) Conforms to structure
Identification (HPLC) Conforms to reference
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 5.0%
Residue on Ignition ≤ 0.5%
Heavy Metals ≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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