Description

1-(4-Nitrophenyl)Cyclobutanecarbonitrile is a high-purity, advanced pharmaceutical intermediate characterized by its unique cyclobutane ring structure. This compound matters for its critical role as a versatile building block in the synthesis of complex, bioactive molecules, enabling the development of new therapeutic agents. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in medicinal chemistry, process development, and the production of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Serves as a critical starting material or intermediate in the scale-up and optimization of API manufacturing routes.
• Agrochemical Synthesis: Potential intermediate for developing new crop protection agents and pesticides due to its nitrophenyl moiety.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	1-(4-Nitrophenyl)Cyclobutanecarbonitrile
CAS No.	1236409-69-0
Molecular Formula	C11H10N2O2
Molecular Weight	202.21 g/mol
Synonyms	4-(Cyclobutylcarbonitrile)nitrobenzene; 1-(4-Nitrophenyl)cyclobutanecarbonitrile; p-Nitrophenylcyclobutanecarbonitrile; Cyclobutanecarbonitrile, 1-(4-nitrophenyl)-; 4-Nitro-α-cyclobutylbenzenecarbonitrile
EINECS	Contact for details

Quality Control

Our 1-(4-Nitrophenyl)Cyclobutanecarbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We adhere to cGMP guidelines where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.