Description

Fmoc-3-Styryl-Dl-Alanine is a non-natural, protected amino acid derivative designed for advanced peptide synthesis. This compound is a critical building block for introducing the unique styryl side chain, which can impart specific structural and functional properties to synthetic peptides. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel peptide-based therapeutics, diagnostics, and biochemical probes. The product is supplied under stringent quality control to ensure optimal performance in sensitive solid-phase peptide synthesis (SPPS) applications.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key Fmoc-protected amino acid for the automated synthesis of custom peptides containing the styryl-alanine moiety.
• Medicinal Chemistry Research: For the design and construction of peptide libraries to screen for new biological activity, particularly in drug discovery programs.
• Bioconjugation & Probe Development: The styryl group can serve as a handle for further chemical modification or as a fluorescent probe component when incorporated into peptides.
• Structural Biology Studies: Used to synthesize peptide analogs to study the impact of hydrophobic, rigid side chains on protein folding and stability.
• Material Science: Incorporation into bio-inspired polymers and materials where the aromatic styryl group influences self-assembly and material properties.

Basic Information

Product Name	Fmoc-3-Styryl-Dl-Alanine
CAS No.	1236297-38-3
Molecular Formula	C26H23NO4
Molecular Weight	413.47 g/mol
Synonyms	Fmoc-3-(2-phenylethenyl)-DL-alanine; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-phenylethenyl)-DL-alanine; Fmoc-Sta(Dl)-OH; Fmoc-β-Styryl-DL-alanine; (RS)-2-(((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-phenylethenyl)propanoic acid
EINECS	Contact for details

Quality Control

Every batch of Fmoc-3-Styryl-Dl-Alanine is manufactured and tested to meet exacting standards for peptide synthesis. Our quality assurance protocol includes comprehensive analytical techniques such as HPLC, NMR, and mass spectrometry to verify identity, purity, and absence of critical impurities. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to ensure full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.