Description

Fmoc-β-(2-Furyl)-Ddl-Alanine CAS NO 1236257-99-0 is a non-natural, protected amino acid derivative featuring a furan side chain, designed for advanced peptide synthesis. This specialized building block is critical for introducing structural diversity and novel properties into synthetic peptides, enabling the development of peptide-based therapeutics and research tools. It is primarily utilized by pharmaceutical R&D departments, biotechnology companies, and academic research laboratories focused on peptide chemistry, drug discovery, and material science.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected amino acid for the Fmoc-strategy, used to incorporate the unique β-(2-furyl)-alanine moiety into peptide chains.
• Peptidomimetic Drug Discovery: Serves as a crucial intermediate for creating peptide analogs and mimetics with enhanced stability, bioavailability, or target affinity.
• Chemical Biology Research: Used in the synthesis of labeled peptides, peptide libraries for screening, and probes to study protein-protein interactions.
• Development of Novel Bioconjugates: The furyl group can serve as a handle for further chemical modification or conjugation in bioconjugate chemistry.
• Academic & Industrial R&D: Essential for fundamental research in organic synthesis, medicinal chemistry, and the exploration of new peptide architectures.

Basic Information

Product Name	Fmoc-β-(2-Furyl)-Ddl-Alanine
CAS No.	1236257-99-0
Molecular Formula	C₂₂H₁₉NO₅
Molecular Weight	377.39 g/mol
Synonyms	Fmoc-β-(2-Furyl)-Ddl-Ala-OH; N-[(9H-Fluoren-9-ylmethoxy)carbonyl]-3-(2-furyl)-Ddl-alanine; Fmoc-3-(2-Furyl)-Ddl-alanine; Fmoc-Ddl-(2-Furyl)Ala-OH; (R,S)-N-Fmoc-3-(2-furyl)alanine; Fmoc-(2-Furyl)Ala-OH (Ddl); N-Fmoc-β-(2-furyl)alanine
EINECS	Contact for details

Quality Control

Every batch of Fmoc-β-(2-Furyl)-Ddl-Alanine is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive peptide synthesis. A Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), identity confirmation, and impurity profile is supplied with each shipment to guarantee batch-to-batch consistency and reliability for your critical research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.