Description

1-(4-Cyanobenzyl)Azetidine-3-Carboxylic Acid is a versatile heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and bioactive molecules, particularly those targeting the central nervous system. Pharmaceutical researchers and fine chemical manufacturers need this high-purity intermediate for constructing complex molecular architectures in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel drug candidates, particularly in neuroscience and oncology research.
• Protease Inhibitor Synthesis: Used in the construction of molecules designed to inhibit specific enzymes.
• Ligand for Receptor Targeting: Serves as a core structure for developing ligands that target G-protein-coupled receptors (GPCRs) and other biological targets.
• Peptidomimetic Chemistry: The azetidine carboxylic acid moiety is valuable for creating conformationally constrained peptide analogs.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological pathways and protein function.
• Agrochemical Research: Potential intermediate for the synthesis of new active ingredients with specific biological activity.
• Material Science: Can be utilized in the synthesis of specialty polymers and functional materials.

Basic Information

Item	Details
Product Name	1-(4-Cyanobenzyl)Azetidine-3-Carboxylic Acid
CAS No.	1236144-55-0
Molecular Formula	C12H12N2O2
Molecular Weight	216.24 g/mol
Synonyms	1-[(4-Cyanophenyl)methyl]azetidine-3-carboxylic acid; 3-Azetidinecarboxylic acid, 1-[(4-cyanophenyl)methyl]-; 1-(4-Cyanobenzyl)azetidine-3-carboxylic acid; Azetidine-3-carboxylic acid, 1-(4-cyanobenzyl)-; 1-(4-Cyanobenzyl)-3-carboxyazetidine; 1-(p-Cyanobenzyl)azetidine-3-carboxylic acid; (1-(4-Cyanobenzyl)azetidin-3-yl)carboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(4-Cyanobenzyl)Azetidine-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our commitment to quality supports applications in cGMP and non-GMP pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for high-purity grades. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.