Description

3-[2-(2-Iodoethoxy)-Ethoxy]-Propyne is a specialized organic building block featuring a terminal alkyne group linked to an iodoether chain. This unique bifunctional structure makes it a valuable reagent for click chemistry, particularly in Huisgen 1,3-dipolar cycloaddition reactions, enabling the synthesis of complex triazole-linked architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel compounds, bioconjugates, and functional polymers.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing triazole-containing drug candidates via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Bioconjugation: Used for site-specific labeling of biomolecules (proteins, peptides, oligonucleotides) with fluorescent dyes, affinity tags, or other functional moieties.
• Polymer & Materials Science: Serves as a functional monomer or cross-linker for creating advanced polymers with tailored properties for coatings, adhesives, or hydrogels.
• Agrochemical Research: Employed in the discovery and synthesis of novel active ingredients with potential herbicidal or pesticidal activity.
• Chemical Probe Development: Facilitates the creation of molecular probes for studying biological pathways and target engagement in R&D.
• Ligand & Catalyst Synthesis: Useful for constructing complex ligand frameworks for catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	3-[2-(2-Iodoethoxy)-Ethoxy]-Propyne
CAS No.	1234387-33-7
Molecular Formula	C7H11IO2
Molecular Weight	254.07 g/mol
Synonyms	1-(2-(2-Iodoethoxy)ethoxy)-2-propyne; 2-Propyne, 3-[2-(2-iodoethoxy)ethoxy]-; Propargyl 2-(2-iodoethoxy)ethyl ether; Iodo-PEG2-propargyl ether; 2-(2-Iodoethoxy)ethyl propargyl ether; PEG2-Iodo-Alkyne; Alkyne-PEG2-Iodide
EINECS	Contact for details

Quality Control

Our 3-[2-(2-Iodoethoxy)-Ethoxy]-Propyne is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC analysis, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.