Description

2-(4-(Difluoromethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is a high-purity boronic ester derivative, a crucial building block in modern synthetic organic chemistry. Its value lies in enabling efficient and selective cross-coupling reactions, which are fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-quality intermediates for drug discovery and specialty chemical synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides with improved efficacy and environmental profiles.
• Liquid Crystal & OLED Materials: Serves as a building block for creating organic electronic materials used in displays and lighting technologies.
• Polymer Chemistry: Employed in the synthesis of functionalized polymers and dendrimers with specific optical or electronic properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating compound libraries.
• Fluorinated Compound Synthesis: The difluoromethylphenyl moiety makes it valuable for introducing fluorine atoms into target molecules to modulate their bioavailability and metabolic stability.

Basic Information

Product Name	2-(4-(Difluoromethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane
CAS No.	1234319-14-2
Molecular Formula	C13H17BF2O2
Molecular Weight	254.09 g/mol
Synonyms	4-(Difluoromethyl)phenylboronic acid pinacol ester; (4-(Difluoromethyl)phenyl)boronic acid pinacol ester; 1,3,2-Dioxaborolane, 2-[4-(difluoromethyl)phenyl]-4,4,5,5-tetramethyl-; 2-(4-(Difluoromethyl)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol (4-(Difluoromethyl)phenyl)boronate; 4-Difluoromethylphenylboronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 2-(4-(Difluoromethyl)Phenyl)-4,4,5,5-Tetramethyl-1,3,2-Dioxaborolane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis, to ensure high purity and batch-to-batch consistency suitable for sensitive applications like pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage or after opening to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.